SMase-IN-1

CAT: 0931-T204131-01Size: 10 mgDry Ice: NoHazardous: No

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CAT#:0931-T204131-01Size:10 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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CAS Number

33017-85-5

Target

Cholinesterase (ChE), Phospholipase, Antibacterial

Related Pathways

Neuroscience, Metabolism, Microbiology/Virology

Bioactivity

SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase (SMase) inhibitor with an IC50 value of 6.43 μM against Bacillus cereus SMase. It also inhibits eqBuChE with an inhibition rate of 59.50% at a concentration of 50 μM. SMase-IN-1 forms a complex with Cu2+ through bio-metal interactions and can inhibit hemolysis of sheep red blood cells induced by Bacillus cereus.

Smiles

O=C1NC(=S)NC2=CC=C(Cl)C=C12

Molecular Formula

C8H5ClN2OS

Molecular Weight

212.656

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

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Alternative Products

Catalog	Name
GTR19250538-01	SMase-IN-1
sc-377135	N-SMase (B-1)
sc-377135 AC	N-SMase (B-1) AC
sc-377135 PE	N-SMase (B-1) PE
sc-377135 P	N-SMase (B-1) P
sc-377135 HRP	N-SMase (B-1) HRP
sc-377135 FITC	N-SMase (B-1) FITC
sc-377135 AF488	N-SMase (B-1) Alexa Fluor® 488
sc-60151	Alk-SMase siRNA (h)
sc-106277-PR	N-SMase (h) -PR

SMase-IN-1

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