TAK-756

CAT: 0804-HY-169949Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-169949Size:1 Each
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PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
TAK-756 is a TAK1 inhibitor with good selectivity for IRAK1/4 and excellent intra-articular pharmacokinetic properties. TAK1 is a potential molecular target for osteoarthritis (OA) with complementary anti-catabolic and anti-inflammatory effects[1].
UNSPSC
12352005
Target
MAP3K
Related Pathways
MAPK/ERK Pathway
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC(C2=NOC(C3=CC(CN4C)=C(C=C3O[C@@H]5CC[C@@H](CC5)O)C4=O)=C2)=CC=C1)N
Molecular Formula
C25H25N3O5
Molecular Weight
447.48
References & Citations
[1]Langlois JB, et al. Identification of TAK-756, A Potent TAK1 Inhibitor for the Treatment of Osteoarthritis through Intra-Articular Administration. J Med Chem. 2024 Dec 12;67 (23) :21163-21185.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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