RET ligand-2

CAT: 0804-HY-168868Size: 1 EachDry Ice: NoHazardous: No

1 / 1

CAT#:0804-HY-168868Size:1 Each

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Description

RET ligand-2 is a selective RET inhibitor. RET ligand-2 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC RET degraders with antitumor activity. RET ligand-2 can be used for the synthesis of RD-23.

CAS Number

3053537-08-6

UNSPSC

12352005

Target

Ligands for Target Protein for PROTAC; RET

Related Pathways

PROTAC; Protein Tyrosine Kinase/RTK

Field of Research

Cancer

Smiles

COC1=NC=C(C=C1)CN2C3CC2CN(C3)C4=NC=C(C=C4)C5=CC(N6CC=C(CC6)N7CCNCC7)=CN8N=CC(C#N)=C58

Molecular Formula

C34H38N10O

Molecular Weight

602.73

References & Citations

[1]Hualong M, et al. Discovery of a Selective and Orally Bioavailable RET Degrader with Effectiveness in Various Mutations. J Med Chem. 2025 Jan 7.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Related Products

Catalog	Name
HY-170373	RET ligand-1
HY-179308	RET ligand-5
HY-170856	RET ligand-4
HY-170853	RET ligand-3
HY-170854	RET Ligand-Linker Conjugate-1
HY-148742-01	RET-IN-21
HY-112950	RET-IN-1
HY-145024	RET-IN-6
HY-153676-01	RET-IN-23
HY-133553-01	RET-IN-3

Alternative Products

Catalog	Name
T211189-01	PRMT5 ligand 2
T207036-01	LC3B ligand 2
T206678-01	TYK2 ligand 2
T206490-01	PIN1 ligand-2
T203383-01	FLT3 ligand-2
T201836-01	HPK1 ligand 2
T200021-01	BCL6 ligand-2
T60279-01	GID4 Ligand 2
GTR19240430-01	STING ligand-2
GTR19235429-01	EGFR ligand-2

RET ligand-2

Related Products

Alternative Products

Popular Products