LIN28-IN-2

• Description:

  LIN28-IN-2 (Compound Ln268) blocks the binding of the zinc finger domain (ZKD) of Lin28 to RNA substrates, and inhibits Lin28a and Lin28b. LIN28-IN-2 inhibits the proliferation of Lin28-positive cancer cell and spheroid growth[1].

• UNSPSC:

  12352005

• Target:

  DNA/RNA Synthesis

• Related Pathways:

  Cell Cycle/DNA Damage

• Field of Research:

  Cancer

• Purity:

  99.51

• Smiles:

  FC1=CC=C(NC(N2)=CSC2=O)C(O)=C1

• Molecular Formula:

  C9H7FN2O2S

• Molecular Weight:

  226.23

• References & Citations:

  [1]Matias-Barrios VM, et al., Developing novel Lin28 inhibitors by computer aided drug design. Cell Death Discov. 2025 Jan 12;11 (1) :5.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported