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LIN28-IN-1

CAT: 0931-T81932-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0931-T81932-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Target
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Bioactivity
LIN28-IN-1 (compound 5) is a selective inhibitor targeting the RNA-binding protein LIN28, binding specifically to its cold shock domain (CSD) . This compound interrupts the LIN28-let-7 miRNA interaction with an IC50 of 5.4 μM, mitigating LIN28's adverse effects on epigenetic gene control. LIN28-IN-1 also exhibits significant anti-proliferative activity against LIN28-expressing JAR cancer cells, with an IC50 value of 6.4 μM [1].
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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