Relebactam-d9

• Description:

  Relebactam-d9 (MK-7655-d9) is deuterium labeled Relebactam. Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1].

• Product Name Alternative:

  MK-7655-d9

• UNSPSC:

  12352005

• Target:

  Bacterial; Beta-lactamase; Isotope-Labeled Compounds

• Related Pathways:

  Anti-infection; Others

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Infection

• Smiles:

  O=S(ON1[C@]2([H])CC[C@@H](C(NC3([2H])C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])=O)[N@@](C2)C1=O)(O)=O

• Molecular Formula:

  C12H11D9N4O6S

• Molecular Weight:

  357.43

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59 (8) :5029-31.|[3]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46 (5) :483-93.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported