Relebactam

• Description :

  Relebactam is a diazabicyclooctane inhibitor with activity against a wide spectrum of β-lactamases, including class A (extended-spectrum β-lactamases and KPC) and class C (AmpC) enzymes. Relebactam shows antibacterial activity[1].

• Product Name Alternative :

  MK-7655

• UNSPSC :

  12352005

• Hazard Statement :

  H315, H319, H320

• Target :

  Bacterial; Beta-lactamase

• Type :

  Reference compound

• Related Pathways :

  Anti-infection

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Infection

• Assay Protocol :

  https://www.medchemexpress.com/Relebactam.html

• Purity :

  99.86

• Solubility :

  DMSO : 175 mg/mL (ultrasonic) |H2O : 50 mg/mL (ultrasonic)

• Smiles :

  O=S(ON1[C@]2([H])CC[C@@H](C(NC3CCNCC3)=O)[N@@](C2)C1=O)(O)=O

• Molecular Formula :

  C12H20N4O6S

• Molecular Weight :

  348.38

• Precautions :

  H315, H319, H320

• References & Citations :

  [1]Lapuebla A, et al. Activity of Imipenem with Relebactam against Gram-Negative Pathogens from New York City. Antimicrob Agents Chemother. 2015 Aug;59 (8) :5029-31.|[2]Bush K. A resurgence of β-lactamase inhibitor combinations effective against multidrug-resistant Gram-negative pathogens. Int J Antimicrob Agents. 2015 Nov;46 (5) :483-93.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  Launched

• CAS Number :

  [1174018-99-5]