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Phenformin (Standard)

CAT: 0804-HY-16397R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-16397R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Phenformin (Standard) is the analytical standard of Phenformin. This product is intended for research and analytical applications. Phenformin (1-phenethylbiguanide) is an orally active antidiabetic and anticancer agent. Phenformin has an incidence of associated lactic acidosis. Phenformin acts through acting AMPK activation and blocking mTOR pathway. Phenformin is also a substrate of P-glycoprotein (P-gp), and an OXPHOS inhibitor. Phenformin induces cancer cell apoptosis[1][2].
CAS Number
114-86-3
UNSPSC
12352100
Target
AMPK; Apoptosis; Mitochondrial Metabolism; Reference Standards
Related Pathways
Apoptosis; Epigenetics; Metabolic Enzyme/Protease; Others; PI3K/Akt/mTOR
Field of Research
Cancer; Metabolic Disease
Smiles
NC(NC(NCCC1=CC=CC=C1)=N)=N
Molecular Formula
C10H15N5
Molecular Weight
205.26
References & Citations
[1]García Rubiño ME, et al. Phenformin as an Anticancer Agent: Challenges and Prospects. Int J Mol Sci. 2019 Jul 5;20 (13) :3316.|[2]Yendapally R, et al. A review of phenformin, metformin, and imeglimin. Drug Dev Res. 2020 Jun;81 (4) :390-401.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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