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MRS4608

CAT: 0804-HY-156203Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-156203Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MRS4608 (Compound 17) is a selective P2Y14 receptor antagonist with IC50 values of 20 (hP2Y14R) and 21.4 nM (mP2Y14R) . MRS4608 has anti-inflammatory activity and can reduce the infiltration of eosinophils. MRS4608 can be used for the researches of inflammation and immunology, such as asthma[1].
CAS Number
[2370976-04-6]
UNSPSC
12352005
Target
P2Y Receptor
Related Pathways
GPCR/G Protein
Field of Research
Inflammation/Immunology
Smiles
O=C(C1=CC2=C(C(C3=CC=C(C45CCN(CC5)CC4)C=C3)=C1)C=CC(C6=CC=C(C(F)(F)F)C=C6)=C2)O
Molecular Formula
C31H26F3NO2
Molecular Weight
501.54
References & Citations
[1]Jung YH, et al. Exploration of Alternative Scaffolds for P2Y14 Receptor Antagonists Containing a Biaryl Core. J Med Chem. 2020 Sep 10;63 (17) :9563-9589.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
P2Y14 Receptor

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