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MRS4596-d4

CAT: 0804-HY-151546SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-151546SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MRS4596-d4 is the deuterium labeled MRS4596. MRS4596 is a potent and selective P2X4 receptor antagonist with an IC50 value of 1.38 μM for human P2X4 receptor. MRS4596 has neuroprotective and neuro-rehabilitative activities in ischemic stroke model. MRS4596 can be used in research of ischemic stroke[1].
UNSPSC
12352005
Target
Isotope-Labeled Compounds; P2X Receptor
Related Pathways
Membrane Transporter/Ion Channel; Others
Field of Research
Neurological Disease
Smiles
O=C(C1)NC(C2=CC=C(C=C2C=C3)C)=C3N(C4=C([2H])C([2H])=C([2H])C(C([N-]5)=NOC5=S)=C4[2H])C1=O.[Na+]
Molecular Formula
C22H11D4N4NaO3S
Molecular Weight
442.46
References & Citations
[1]Toti KS, et al. Structure-Activity Relationship and Neuroprotective Activity of 1,5-Dihydro-2H-naphtho[1,2-b][1,4]diazepine-2,4 (3H) -diones as P2X4 Receptor Antagonists. J Med Chem. 2022 Sep 23.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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