(E) -XS-060

CAT: 0804-HY-149085ASize: 1 EachDry Ice: NoHazardous: No

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Description

(E) -XS-060 is an isomer of XS-060. XS-060 is a RXRα antagonist. XS-060 inhibits pRXRα-PLK1 interaction. XS-060 induces RXRα-dependent mitotic arrest. XS-060 exhibits good antitumor activity against breast cancer, lung adenocarcinoma, and liver cancer[1].

CAS Number

2787626-06-4

UNSPSC

12352005

Target

RAR/RXR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Field of Research

Cancer

Smiles

COC(C=C1)=CC=C1CC(N/N=C/C2=C(O)C=CC3=C2C=CC=C3)=O

Molecular Formula

C20H18N2O3

Molecular Weight

334.37

References & Citations

[1]Chen J, et al. Discovery of bipyridine amide derivatives targeting pRXRα-PLK1 interaction for anticancer therapy. Eur J Med Chem. 2023 Jun 5;254:115341.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

RXRα

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Alternative Products

Catalog	Name
C8555-100	XS-060
MBS5766396	CP-060
B5056-10	L-733,060 hydrochloride
GTR17689270	Bcl-XS/BCL2L1/XS Rabbit Polyclonal Antibody
MBS1334250-01	Recombinant Neurospora crassa Uncharacterized protein B2A19.060 (B2A19.060, NCU21521)
GTR18731984	Bcl-XS/BCL2L1/XS Rabbit Polyclonal Antibody (Fluoro488)
GTR18731981	Bcl-XS/BCL2L1/XS Rabbit Polyclonal Antibody (Fluoro647)
ASA-B0204	Bcl-XS Antibody
GN1801XL	Nitrile Gloves, XS
MBS6010506-01	Bcl-XL, XS

(E) -XS-060

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