CatD-IN-1

• Description :

  CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM. CatD-IN-1 holds potential for research in the field of osteoarthritis [1].

• CAS Number :

  [1628521-28-7]

• UNSPSC :

  12352005

• Target :

  Cathepsin

• Related Pathways :

  Metabolic Enzyme/Protease

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology

• Concentration :

  10mM

• Purity :

  99.27

• Solubility :

  DMSO : 50 mg/mL (ultrasonic)

• Smiles :

  O=C(CC1=CC(OC)=C(C=C1[N+]([O-])=O)OC)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N

• Molecular Formula :

  C18H18Cl2N4O5

• Molecular Weight :

  441.27

• References & Citations :

  [1]Grädler U, et al. Structure-based optimization of non-peptidic Cathepsin D inhibitors. Bioorg Med Chem Lett. 2014 Sep 1;24 (17) :4141-50.

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  -20°C, 3 years (Powder)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported