CatD-IN-1

• Description:

  CatD-IN-1 (Compound 5) is a Cathepsin D inhibitor with an IC50 of 0.44 μM. CatD-IN-1 holds potential for research in the field of osteoarthritis [1].

• UNSPSC:

  12352005

• Target:

  Cathepsin

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Concentration:

  10mM

• Purity:

  99.27

• Solubility:

  DMSO : 50 mg/mL (ultrasonic)

• Smiles:

  O=C(CC1=CC(OC)=C(C=C1[N+]([O-])=O)OC)NC(NCC2=CC=C(C(Cl)=C2)Cl)=N

• Molecular Formula:

  C18H18Cl2N4O5

• Molecular Weight:

  441.27

• References & Citations:

  [1]Grädler U, et al. Structure-based optimization of non-peptidic Cathepsin D inhibitors. Bioorg Med Chem Lett. 2014 Sep 1;24 (17) :4141-50.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C, 3 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  1628521-28-7