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CatB-IN-1

CAT: 0804-HY-116264Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-116264Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
CatB-IN-1 is an enzyme inhibitor with significant inhibitory activity against tumor invasion. CatB-IN-1 may reduce the invasiveness of tumor cells by regulating intracellular protein metabolism. CatB-IN-1 demonstrates effective anti-invasive ability in cell models and can significantly reduce the invasive ability of MCF-10A neoT cells. The structure-activity relationship study of CatB-IN-1 shows that its design can target multiple functions of cat hepsin B[1].
CAS Number
1417737-67-7
UNSPSC
12352005
Target
Ser/Thr Protease
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/catb-in-1.html
Smiles
N#CCNCC1=CC([N+]([O-])=O)=C2C=CC=NC2=C1O
Molecular Formula
C12H10N4O3
Molecular Weight
258.23
References & Citations
[1]Development of new cathepsin B inhibitors: combining bioisosteric replacements and structure-based design to explore the structure-activity relationships of nitroxoline derivatives
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported