Products for Research Use Only

Mirabegron-d5

CAT: 0804-HY-14773S3Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-14773S3Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Mirabegron-d5 (YM178-d5) is deuterium labeled Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.
CAS Number
1258889-45-0
Product Name Alternative
YM178-d5
UNSPSC
12352005
Target
Adrenergic Receptor; Isotope-Labeled Compounds
Related Pathways
GPCR/G Protein; Neuronal Signaling; Others
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Neurological Disease; Endocrinology; Cancer
Smiles
NC1=NC(CC(NC2=CC=C(C=C2)CCNC[C@@H](C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])O)=O)=CS1
Molecular Formula
C21H19D5N4O2S
Molecular Weight
401.54
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Takasu T, et al. Effect of (R) -2- (2-aminothiazol-4-yl) -4'-{2-[ (2-hydroxy-2-phenylethyl) amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321 (2) :642-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported