Mirabegron-d5

• Description :

  Mirabegron-d5 (YM178-d5) is deuterium labeled Mirabegron. Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.

• Product Name Alternative :

  YM178-d5

• UNSPSC :

  12352005

• Target :

  Adrenergic Receptor; Isotope-Labeled Compounds

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling; Others

• Applications :

  Metabolism-protein/nucleotide metabolism

• Field of Research :

  Neurological Disease; Endocrinology; Cancer

• Smiles :

  NC1=NC(CC(NC2=CC=C(C=C2)CCNC[C@@H](C3=C([2H])C([2H])=C([2H])C([2H])=C3[2H])O)=O)=CS1

• Molecular Formula :

  C21H19D5N4O2S

• Molecular Weight :

  401.54

• References & Citations :

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216.|[2]Takasu T, et al. Effect of (R) -2- (2-aminothiazol-4-yl) -4'-{2-[ (2-hydroxy-2-phenylethyl) amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321 (2) :642-7.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Isotope-Labeled Compounds

• Clinical Information :

  No Development Reported

• CAS Number :

  [1258889-45-0]