Mirabegron

• Description:

  Mirabegron is a selective β3-adrenoceptor agonist with EC50 of 22.4 nM.

• Product Name Alternative:

  YM178

• UNSPSC:

  12352005

• Hazard Statement:

  H361

• Target:

  Adrenergic Receptor

• Type:

  Reference compound

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease; Endocrinology; Cancer

• Assay Protocol:

  https://www.medchemexpress.com/mirabegron.html

• Purity:

  99.90

• Solubility:

  DMSO : 100 mg/mL (ultrasonic)

• Smiles:

  O=C(NC1=CC=C(CCNC[C@H](O)C2=CC=CC=C2)C=C1)CC3=CSC(N)=N3

• Molecular Formula:

  C21H24N4O2S

• Molecular Weight:

  396.51

• Precautions:

  H361

• References & Citations:

  [1]Takasu T, et al. Effect of (R) -2- (2-aminothiazol-4-yl) -4'-{2-[ (2-hydroxy-2-phenylethyl) amino]ethyl} acetanilide (YM178), a novel selective beta3-adrenoceptor agonist, on bladder function. J Pharmacol Exp Ther. 2007 May;321 (2) :642-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• Isoform:

  β adrenergic receptor

• CAS Number:

  223673-61-8