Products for Research Use Only
RegisterLogin

SYUIQ-5

CAT: 0804-HY-145748-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-145748-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
SYUIQ-5 is a G-quadruplex ligand. SYUIQ-5 stabilizes G-quadruplex and induce senescence. SYUIQ-5 inhibits c-myc gene promoter activity. SYUIQ-5 induces cancer cells autophagy by triggering telomere damage through TRF2 delocalization from telomeres[1].
CAS Number
188630-47-9
UNSPSC
12352005
Hazard Statement
H400
Target
Autophagy; c-Myc; G-quadruplex
Related Pathways
Apoptosis; Autophagy; Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
98.0
Smiles
CN(C)CCCNC(C1=C(C=CC=C1)N=C23)=C3NC4=C2C=CC=C4
Molecular Formula
C20H22N4
Molecular Weight
318.42
Precautions
H400
References & Citations
[1]Zhou WJ, et al. G-quadruplex ligand SYUIQ-5 induces autophagy by telomere damage and TRF2 delocalization in cancer cells. Mol Cancer Ther. 2009 Dec;8 (12) :3203-13.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-160457-01FABP4/5-IN-5
HY-1494765-LOX-IN-5
HY-N85815,5'-Dimethoxysecoisolariciresinol
HY-N26485,5'-Dimethoxylariciresinol
HY-1543445′-Deoxy-5′-iodo-5-methyluridine
HY-W037549-015,5,5-Trifluoro-DL-leucine
HY-1543465’-Azido-5’-deoxy-5-methyluridine
HY-1543454′,5′-Didehydro-5′-deoxy-5-methyluridine
HY-D1539-01Cyanine 5.5 azide
HY-D1639A5,5'-Dibromo-BAPTA

Alternative Products

CatalogName
T204617-01SYUIQ-5
sc-2627255,5,5-Trifluorovaleronitrile
234404-015,5,5-Trifluoronorvaline
PDA866615,5,5-Trifluoropentanonitrile
JH2382995,5,5-trifluoroleucine
AKA25347-015,5,5-Trifluoropentanal
TRC-F632600-2.5GN-Fmoc-5,5,5,5',5',5'-Hexafluoro-L-leucine
OR1058406-015,5',5'',5'''-Methanetetrayltetrakis (2-hydroxybenzaldehyde)
459053N-Fmoc-5,5,5,5',5',5'-Hexafluoro-L-leucine discontinued
PC4455-015,5,5-Trifluoropentanoic acid

Popular Products