RyR1-IN-1

CAT: 0804-HY-141564Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-141564Size:1 Each
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Description
RyR1-IN-1 (Compound 1) is a RyR1 inhibitor with an IC50 of 12 nM. RyR1-IN-1 blocks Ca²⁺ release and inhibits muscle tetany caused by caffeine and heat stress. RyR1-IN-1 can completely prevent the increase in body temperature and death caused by isoflurane and heat stress. RyR1-IN-1 can be used for the study of heat stroke[1].
CAS Number
[2837939-81-6]
UNSPSC
12352005
Target
Calcium Channel
Related Pathways
Membrane Transporter/Ion Channel; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C1C(C(O[Na])=O)=CN(CCCCCCCC)C2=CC3=C(OCO3)C=C21
Molecular Formula
C19H22NNaO5
Molecular Weight
367.37
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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