(±) 11 (12) -EET methyl ester

• Description :

  (±) 11 (12) -EET methyl ester (11,12-EET-methyl ester) is a methylated derivative of 11,12-epoxyeicosatrienoic acid (11,12-EET) (HY-130494) . (±) 11 (12) -EET methyl ester cannot induce β-arrestin recruitment of the G protein-coupled receptor GPR132. (±) 11 (12) -EET methyl ester fails to enhance the expression of hematopoietic stem and progenitor cell (HSPC) markers. (±) 11 (12) -EET methyl ester can be used as a negative control molecule to study the structure-function relationship of 11,12-EET, facilitating the analysis of the role of the oxygenated fatty acid-GPR132 signaling axis in hematopoiesis[1].

• Product Name Alternative :

  11,12-EET methyl ester; (±) 11,12-EpETrE methyl ester

• UNSPSC :

  12352211

• Target :

  Drug Derivative

• Related Pathways :

  Others

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Inflammation/Immunology; Cardiovascular Disease

• Smiles :

  CCCCC/C=C\C[C@@H]1[C@H](C/C=C\C/C=C\CCCC(OC)=O)O1

• Molecular Formula :

  C21H34O3

• Molecular Weight :

  334.49

• References & Citations :

  [1]Lahvic JL, et al. Specific oxylipins enhance vertebrate hematopoiesis via the receptor GPR132.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Natural Products

• Clinical Information :

  No Development Reported

• CAS Number :

  [90693-45-1]