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6β-hydroxy Dexamethasone

CAT: 0931-T37361Size: 2500 μgDry Ice: NoHazardous: No
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CAT#:0931-T37361Size:2500 μg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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CAS Number
55879-47-5
Target
Others, Glucocorticoid Receptor
Related Pathways
Others, Endocrinology/Hormones
Bioactivity
6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.
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Molecular Formula
C22H29FO6
Molecular Weight
408.46
Shipping Conditions
Ice Packs
Storage Temperature
-20°C

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