BW A4C

CAT: 0804-HY-136923Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-136923Size:1 Each
Selected
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
BW A4C is a selective 5-lipoxygenase (5-LO) inhibitor. BW A4C is also an inhibitor of linoleic acid 8R-dioxygenase in Gaeumannomyces graminis, with an IC50 value of 0.2 μM. BW A4C can be used in research on diseases such as asthma[1][2].
CAS Number
[106328-57-8]
UNSPSC
12352005
Target
Lipoxygenase
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
CC(N(O)C/C=C/C1=CC=CC(OC2=CC=CC=C2)=C1)=O
Molecular Formula
C17H17NO3
Molecular Weight
283.32
References & Citations
[1]Payne AN, et al. Hydroxamic acids and hydroxyureas as novel, selective 5-lipoxygenase inhibitors for possible use in asthma. Agents Actions Suppl. 1991;34:189-99.|[2]Brodowsky ID, et al. BW A4C and other hydroxamic acids are potent inhibitors of linoleic acid 8R-dioxygenase of the fungus Gaeumannomyces graminis. Eur J Pharmacol. 1994 Mar 11;254 (1-2) :43-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
5-LOX

Popular Products