BW-534U87

CAT: 0804-HY-19130Size: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-19130Size:1 Each
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
BW-534U87 is an orally active adenosine A1 receptor agonist and competitive adenosine deaminase (ADA) inhibitor (Ki=7 μM) . BW-534U87 elevates brain adenosine levels and suppresses epileptiform activity. BW-534U87 demonstrate anticonvulsant efficacy in animal seizure models. BW-534U87 is promising for research of epilepsy and adenosine-related neuropsychiatric disorders[1].
CAS Number
[143153-93-9]
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Adenosine Receptor
Related Pathways
GPCR/G Protein
Field of Research
Neurological Disease
Smiles
FC1=CC=CC(F)=C1CN2N=NC3=C2C=CN=C3N.Cl
Molecular Formula
C12H10ClF2N5
Molecular Weight
297.69
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Southam E, et al. Broad spectrum anticonvulsant activity of BW534U87: possible role of an adenosine-dependent mechanism. Pharmacol Biochem Behav. 2002 Dec;74 (1) :111-8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound2
Clinical Information
Phase 2
Isoform
Adenosine A1 receptor (A1R)

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