Deflazacort-d3-1

• Description:

  Deflazacort-d3-1 is the deuterium labeled Deflazacort (HY-13609) . Deflazacort, a glucocorticoid, is an inactive proagent and is converted rapidly to the active metabolite 21-desacetyldeflazacort. Deflazacort is used as an anti-inflammatory and immunosuppressant[1].

• UNSPSC:

  12352005

• Target:

  Glucocorticoid Receptor; Isotope-Labeled Compounds

• Related Pathways:

  Immunology/Inflammation; Others; Vitamin D Related/Nuclear Receptor

• Applications:

  COVID-19-immunoregulation

• Field of Research:

  Inflammation/Immunology

• Smiles:

  O=C1C=C[C@]2(C(CC[C@@]3([C@@]2([C@]([2H])(C([2H])([C@]4([C@]3(C[C@@]5([C@]4(N=C(O5)C)C(COC(C)=O)=O)[H])[H])C)[2H])O)[H])[H])=C1)C

• Molecular Formula:

  C25H28D3NO6

• Molecular Weight:

  444.54

• References & Citations:

  [1]Mollmann, H., et al., Pharmacokinetic/pharmacodynamic evaluation of deflazacort in comparison to methylprednisolone and prednisolone. Pharmaceutical research, 1995. 12 (7) : p. 1096-1100.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported