GSK343 (Standard)

CAT: 0804-HY-13500RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-13500RSize:1 Each
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Description
GSK343 (Standard) is the analytical standard of GSK343. This product is intended for research and analytical applications. GSK343 is a highly potent and selective EZH2 inhibitor with an IC50 of 4 nM.
CAS Number
[1346704-33-3]
UNSPSC
12352100
Target
Autophagy; Histone Methyltransferase; Reference Standards
Related Pathways
Autophagy; Epigenetics; Others
Field of Research
Cancer
Smiles
O=C(C1=CC(C2=CC(N3CCN(C)CC3)=NC=C2)=CC4=C1C=NN4C(C)C)NCC5=C(CCC)C=C(C)NC5=O
Molecular Formula
C31H39N7O2
Molecular Weight
541.69
References & Citations
[1]Sharad K, et al. Identification of Potent, Selective, Cell-Active Inhibitors of the Histone Lysine Methyltransferase EZH2. ACS Med Chem Lett. 2012 Oct 19;3 (12) :1091-6.|[2]Ding M, et al. The polycomb group protein enhancer of zeste 2 is a novel therapeutic target for cervical cancer. Clin Exp Pharmacol Physiol. 2015 May;42 (5) :458-64.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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Alternative Products

CatalogName
sc-397025GSK343
2365-1EZSolution™ GSK343
A13114-25GSK343 25mg
A13114-10GSK343 10mg
A13114-1GSK343 1mg
A13114-100GSK343 100mg
A13114-50GSK343 50mg
A13114-5GSK343 5mg
bs-60173C-01GSK343 --- EZH2 Methyltransferase Inhibitor
A13114-10mM-DGSK343 10mM * 1mL in DMSO

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