Ionomycin (calcium) (Standard)

• Description :

  2- (1-Piperazinyl) pyrimidine (Standard) is the analytical standard of 2- (1-Piperazinyl) pyrimidine. This product is intended for research and analytical applications. 2- (1-Piperazinyl) pyrimidine is the major metabolite of Tandospirone (HY-14558) [1].

• Product Name Alternative :

  SQ23377 (calcium) (Standard)

• UNSPSC :

  12352005

• Target :

  Antibiotic; Apoptosis; Bacterial; Calcium Channel; PKC; Reference Standards

• Related Pathways :

  Anti-infection; Apoptosis; Epigenetics; Membrane Transporter/Ion Channel; Neuronal Signaling; Others; TGF-beta/Smad

• Field of Research :

  Cancer; Infection

• Smiles :

  O=C([O-])CC[C@@H](C)C[C@H](C)C[C@H](C)C(/C=C([O-])/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@@H](O)[C@@H](C)[C@@H](O)C[C@@H]1CC[C@]([C@@H]2O[C@](C)([C@H](O)C)CC2)(C)O1)=O.[Ca+2]

• Molecular Formula :

  C41H70CaO9

• Molecular Weight :

  747.07

• References & Citations :

  [1]Liu C, et al. Characterization of ionomycin as a calcium ionophore. J Biol Chem. 1978 Sep 10;253 (17) :5892-4.|[2]Chatila T, et al. Mechanisms of T cell activation by the calcium ionophore ionomycin. J Immunol. 1989 Aug 15;143 (4) :1283-9.|[3]Gil-Parrado S, et al. Ionomycin-activated calpain triggers apoptosis. A probable role for Bcl-2 family members. J Biol Chem. 2002 Jul 26;277 (30) :27217-26.|[4]Stoeck A, et al A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. Biochem J. 2006 Feb 1;393 (Pt 3) :609-18.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [56092-82-1]