Products for Research Use Only
RegisterLogin

Levomefolate (calcium) (Standard)

CAT: 0804-HY-17383R-01Size: 5 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-17383R-01Size:5 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Levomefolate (calcium) (Standard) is the analytical standard of Levomefolate (calcium) . This product is intended for research and analytical applications. Levomefolate (calcium) is an orally active, BBB-penetrable and active form of folic acid. Levomefolate (calcium) can be used as a food supplement for folic acid and in the research of neural tube defect diseases[1][2][3][4][5].
CAS Number
151533-22-1
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Antifolate; Reference Standards
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage; Others
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/levomefolate-calcium-standard.html
Purity
98.97
Smiles
O=C([O-])CC[C@@H](C([O-])=O)NC(C1=CC=C(NC[C@@H]2N(C)C3=C(N=C(N)NC3=O)NC2)C=C1)=O.[Ca+2]
Molecular Formula
C20H23CaN7O6
Molecular Weight
497.52
Precautions
H302, H315, H319, H335
References & Citations
[1]Fruzzetti F. Beyaz?: an oral contraceptive fortified with folate. Womens Health (Lond Engl) . 2012 Jan;8 (1) :13-9.|[2]Wiesinger H, Eydeler U, Richard F, et al. Bioequivalence evaluation of a folate-supplemented oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium versus ethinylestradiol/drospirenone and levomefolate calcium alone. Clin Drug Investig. 2012 Oct 1;32 (10) :673-84.|[3]Hartmut Blodea, Christine Klippingb, Frank Richardc, et al. Bioequivalence study of an oral contraceptive containing ethinylestradiol/drospirenone/levomefolate calcium relative to ethinylestradiol/drospirenone and to levomefolate calcium alone. Contraception.2012, 85 (2), :177-184|[4]Rapkin RB, Creinin MD. The combined oral contraceptive pill containing drospirenone and ethinyl estradiol plus levomefolate calcium. Expert Opin Pharmacother. 2011 Oct;12 (15) :2403-10. doi: 10.1517/14656566.2011.610791.|[5]Levomefolic_acid
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards

Chemical Information

Levomefolate Calcium

Levomefolate calcium is an organic calcium salt of (6S)-5-methyltetrahydrofolic acid. It has a role as an antidepressant. It contains a (6S)-5-methyltetrahydrofolate(2-).

CAS Number151533-22-1
PubChem CID135564391
IUPAC Namecalcium (2S)-2-[[4-[[(6S)-2-amino-5-methyl-4-oxo-3,6,7,8-tetrahydropteridin-6-yl]methylamino]benzoyl]amino]pentanedioate
Molecular FormulaC20H23CaN7O6
Molecular Weight497.5
Topological Polar Surface Area204
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Heavy Atom Count34
Formal Charge0
Complexity854
SMILES
CN1[C@H](CNC2=C1C(=O)NC(=N2)N)CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(=O)[O-])C(=O)[O-].[Ca+2]
InChI
InChI=1S/C20H25N7O6.Ca/c1-27-12(9-23-16-15(27)18(31)26-20(21)25-16)8-22-11-4-2-10(3-5-11)17(30)24-13(19(32)33)6-7-14(28)29;/h2-5,12-13,22H,6-9H2,1H3,(H,24,30)(H,28,29)(H,32,33)(H4,21,23,25,26,31);/q;+2/p-2/t12-,13-;/m0./s1
InChIKey
VWBBRFHSPXRJQD-QNTKWALQSA-L
Chemical Structure
2D Structure
2D structure of Levomefolate Calcium
CAS: 151533-22-1
CID: 135564391
Formula: C20H23CaN7O6
MW: 497.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight497.5
Hydrogen Bond Donor Count5
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass497.1335723
Monoisotopic Mass497.1335723
Topological Polar Surface Area204 Ų
Heavy Atom Count34
Formal Charge0
Complexity854
Isotope Atom Count0
Defined Atom Stereocenter Count2
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-17383-01Levomefolate (calcium)
HY-17383S-01Levomefolate-13C5 (calcium)
HY-17383ALevomefolate (disodium)
HY-W145486R-01Calcium gluconate (Standard)
HY-13434ARIonomycin (calcium) (Standard)
HY-17504R-01Rosuvastatin (Calcium) (Standard)
HY-B1092R-01Gluconate (Calcium) (Standard)
HY-111603R-01Calcium dobesilate (Standard)
HY-13667R-01Levoleucovorin (Calcium) (Standard)
HY-17398R-01Mitiglinide (calcium) (Standard)

Alternative Products

CatalogName
MBS3602116-01Levomefolate calcium
89982459Calcium levomefolate
TRC-L375760-75MGent-Levomefolate Calcium
A13668-10Levomefolate Calcium 10mg
T32706Levomefolate calcium pentahydrate
TRC-L375722-25MGLevomefolate Calcium-13C5
A13668-100Levomefolate Calcium 100mg
A13668-50Levomefolate Calcium 50mg
A13668-25Levomefolate Calcium 25mg
A13668-5Levomefolate Calcium 5mg

Popular Products