Rivanicline-d3

CAT: 0804-HY-W745872-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-W745872-01Size:1 mg
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Description
Rivanicline-d3 (RJR-2403-d3) is the deuterium labeled Rivanicline. Rivanicline (RJR-2403) is a neuronal nicotinic receptor agonist.[1][2][3][4][5].
CAS Number
[220088-40-4]
Product Name Alternative
RJR-2403-d3; (E) -Metanicotine-d3
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
[2H]C([2H])(NCC/C=C/C1=CC=CN=C1)[2H]
Molecular Formula
C10H11D3N2
Molecular Weight
165.25
References & Citations
[1]Bencherif M, et al. RJR-2403: a nicotinic agonist with CNS selectivity I. In vitro characterization. J Pharmacol Exp Ther. 1996 Dec;279 (3) :1413-21.|[2]Lippiello PM, et al. RJR-2403: a nicotinic agonist with CNS selectivity II. In vivo characterization. J Pharmacol Exp Ther. 1996 Dec;279 (3) :1422-9.|[3]Damaj MI, et al. Antinociceptive and pharmacological effects of metanicotine, a selective nicotinic agonist. J Pharmacol Exp Ther. 1999 Oct;291 (1) :390-8.|[4]Papke RL, et al The activation and inhibition of human nicotinic acetylcholine receptor by RJR-2403 indicate a selectivity for the alpha4beta2 receptor subtype. J Neurochem. 2000 Jul;75 (1) :204-16. |[5]Rodríguez-Moreno A, et al. The nicotinic agonist RJR-2403 compensates the impairment of eyeblink conditioning produced by the noncompetitive NMDA-receptor antagonist MK-801. Neurosci Lett. 2006 Jul 10;402 (1-2) :102-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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