NAI-802

• Description:

  NAI-802 is a new lantibiotic. NAI-802 can be produced by Actinoplanes sp. NAI-802 shows a significant activity against Gram-positive anaerobic bacteria, such as Clostridium difficile, C. butyricum, C. perfringens and Peptostreptococcus asaccharolyticus with MIC ranges of 0.25-2 μg/mL[1].

• UNSPSC:

  12352005

• Target:

  Bacterial

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Smiles:

  O=C(N[C@H](C(N[C@@H](CSC[C@H]1NC([C@@H](N)C)=O)C(N[C@H]([C@@H](SC[C@](C(NCC(N[C@@]([C@@H]([S](C[C@H]2C(N[C@H](C(O)=O)CCCNC(N)=N)=O)=O)C)([H])C(N[C@H]3C(C)C)=O)=O)=O)([H])NC([C@@H](NC4=O)CCC(O)=O)=O)C)C(N[C@H](C(N[C@@]([C@@H](SC[C@](C(N[C@H](C(N2)=O)C)=O)([H])NC([C@](NC3=O)([H])[C@@H](C)CC)=O)C)([H])C(N[C@@]4([H])[C@@H](C)CC)=O)=O)CC(C)C)=O)=O)=O)C(C)C)[C@](NC(CNC([C@](NC1=O)([H])CO)=O)=O)([H])CC5=CNC6=CC=CC=C56

• Molecular Formula:

  C90H141N25O26S4

• Molecular Weight:

  2117.49

• References & Citations:

  [1]Simone M, et al. Isolation and characterization of NAI-802, a new lantibiotic produced by two different Actinoplanes strains. J Antibiot (Tokyo) . 2013 Feb;66 (2) :73-8.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1426209-02-0]