(S) -MCOPPB

• Description :

  (S) -MCOPPB is the S-form of MCOPPB (HY-13101) . MCOPPB is an orally active and selective agonist of Nociceptin/Orphanin FQ-Receptor. MCOPPB inhibits signaling through the NOP receptor in the mouse brain. MCOPPB can be used for anxiety disorders study[1].

• UNSPSC :

  12352005

• Target :

  Opioid Receptor

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling

• Applications :

  Neuroscience-Neuromodulation

• Field of Research :

  Neurological Disease

• Purity :

  98.97

• Solubility :

  DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)

• Smiles :

  CC1(CCCCCCC1)N2CCC(CC2)N3C([C@H]4CCCNC4)=NC5=CC=CC=C53

• Molecular Formula :

  C26H40N4

• Molecular Weight :

  408.62

• References & Citations :

  [1]Hayashi S, et al. Novel non-peptide nociceptin/orphanin FQ receptor agonist, 1-[1- (1-Methylcyclooctyl) -4-piperidinyl]-2-[ (3R) -3-piperidinyl]-1H-benzimidazole: design, synthesis, and structure-activity relationship of oral receptor occupancy in the brain for orally potent antianxiety drug. J Med Chem. 2009 Feb 12;52 (3) :610-25.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  4°C (Powder, protect from light)

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported

• CAS Number :

  [1108147-70-1]