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Etrasimod-d9

CAT: 0804-HY-12789SSize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-12789SSize:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Etrasimod-d9 (APD334-d9) is a deuterium labeled Etrasimod. Etrasimod (APD334) is a potent, selective and orally available antagonist of the sphingosine-1-phosphate-1 (S1P1) receptor with an IC50 value of 1.88 nM in CHO cells.[1].
Product Name Alternative
APD334-d9
UNSPSC
12352005
Target
Isotope-Labeled Compounds; LPL Receptor
Related Pathways
GPCR/G Protein; Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
FC(F)(F)C1=CC(COC2=CC=C(NC3=C4CC[C@@H]3CC(O)=O)C4=C2)=CC=C1C5([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C5([2H])[2H]
Molecular Formula
C26H17D9F3NO3
Molecular Weight
466.54
References & Citations
[1]Buzard DJ, et al. Discovery of APD334: Design of a Clinical Stage Functional Antagonist of the Sphingosine-1-phosphate-1 Receptor. ACS Med Chem Lett. 2014 Nov 4;5 (12) :1313-7.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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