DHPG (Standard)

• Description :

  DHPG (Standard) is the analytical standard of DHPG. This product is intended for research and analytical applications. DHPG is the agonist for mGluR 1/5 (EC50 for mGluR 1 is 60 nM) that activates the phospholipase C (PLC) pathway, and leads ultimately to the activation of protein kinase C (PKC) [1].

• UNSPSC :

  12352100

• Target :

  MGluR; Reference Standards

• Related Pathways :

  GPCR/G Protein; Neuronal Signaling; Others

• Field of Research :

  Neurological Disease

• Smiles :

  O=C(O)C(N)C1=CC(O)=CC(O)=C1

• Molecular Formula :

  C8H9NO4

• Molecular Weight :

  183.16

• References & Citations :

  [1]Winder DG, et al. Metabotropic glutamate receptor (mGluR) -mediated potentiation of cyclic AMP responses does not require phosphoinositide hydrolysis: mediation by a group II-like mGluR. J Neurochem. 1995 Feb;64 (2) :592-9.|[2]Pellegrini-Giampietro DE, et al. Pharmacological characterization of metabotropic glutamate receptors coupled to phospholipase D in the rat hippocampus. Br J Pharmacol. 1996 Jun;118 (4) :1035-43.|[3]Scotland PE, et al., Enhanced 3,5-dihydroxyphenylglycine-induced sustained nociceptive behaviors in rats with neuropathy or chronic inflammation. Behav Brain Res. 2007 Dec 3;184 (2) :150-6.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference Standards

• CAS Number :

  [146255-66-5]