Products for Research Use Only
RegisterLogin

2-Hydroxymethyl olanzapine

CAT: 0804-HY-125446Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-125446Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
2-Hydroxymethyl olanzapine is a metabolite and a degradation product of Olanzapine[2].
CAS Number
174756-45-7
Product Name Alternative
LY-290411; 2-OH-OLZ
UNSPSC
12352005
Target
Drug Metabolite
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Others
Purity
98.45
Smiles
OCC1=CC2=C(NC3=CC=CC=C3N=C2N4CCN(CC4)C)S1
Molecular Formula
C17H20N4OS
Molecular Weight
328.43
References & Citations
[1]Chiu JA, et al. Analysis and pharmacokinetics of olanzapine (LY170053) and two metabolites in rat plasma using reversed-phase HPLC with electrochemical detection. J Pharm Biomed Anal. 1996 Mar;14 (5) :609-615.|[2]Saar E, et al. Identification of 2-hydroxymethyl-olanzapine as a novel degradation product of olanzapine. Forensic Sci Int. 2012 Jul 10;220 (1-3) :74-9.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Chemical Information

4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol

2-hydroxymethylolanzapine is a benzodiazepine.

CAS Number174756-45-7
PubChem CID135515431
IUPAC Name[4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepin-2-yl]methanol
Molecular FormulaC17H20N4OS
Molecular Weight328.4
XLogP1.6
Topological Polar Surface Area79.3
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Heavy Atom Count23
Formal Charge0
Complexity452
SMILES
CN1CCN(CC1)C2=NC3=CC=CC=C3NC4=C2C=C(S4)CO
InChI
InChI=1S/C17H20N4OS/c1-20-6-8-21(9-7-20)16-13-10-12(11-22)23-17(13)19-15-5-3-2-4-14(15)18-16/h2-5,10,19,22H,6-9,11H2,1H3
InChIKey
FPDIERBPQFAFSI-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 4-(4-Methyl-1-piperazinyl)-10H-thieno(2,3-b)(1,5)benzodiazepine-2-methanol
CAS: 174756-45-7
CID: 135515431
Formula: C17H20N4OS
MW: 328.4
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight328.4
XLogP31.6
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count5
Rotatable Bond Count2
Exact Mass328.13578245
Monoisotopic Mass328.13578245
Topological Polar Surface Area79.3 Ų
Heavy Atom Count23
Formal Charge0
Complexity452
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-14541-01Olanzapine
HY-W004412-01Olanzapine-lactam
HY-Z4467-01Olanzapine thiolactam
HY-14541S-01Olanzapine-d3
HY-Z4466-01Olanzapine ketolactam
HY-14541AOlanzapine (hydrochloride)
HY-14541R-01Olanzapine (Standard)
HY-14541S1Olanzapine-d4
HY-14541S2Olanzapine-d8
HY-W004412ROlanzapine-lactam (Standard)

Alternative Products

CatalogName
FH24394-012-Hydroxymethyl olanzapine
279455-012-Hydroxymethyl olanzapine discontinued
CS-T-964052-Hydroxymethyl Olanzapine-d3 (Major)
0140642-Hydroxymethyl Olanzapine-d3 (Major) discontinued
RM-O122628-01Olanzapine Impurity 2
TRC-O253772-1MGOlanzapine-d3 2-Carboxaldehyde
CS-O-44692N-Desmethyl N-Nitroso Olanzapine impurity 2
AR-O08908-01N-Nitroso N-Desmethyl Olanzapine impurity 2
TRC-A622420-100MG2-[(2-Aminophenyl)amino]-5-methyl-3-thiophenecarbonitrile(Olanzapine Impurity)
TRC-D292675-25MG4-Des(4-methyl-1-piperazinyl)-4-(((2-aminoethyl)amino)methanol) Olanzapine

Popular Products