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Olanzapine-d3

CAT: 0804-HY-14541S-01Size: 1 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-14541S-01Size:1 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Olanzapine-d3 is the deuterium labeled Olanzapine. Olanzapine is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptors (Ki=19 nM) . Olanzapine is an atypical antipsychotic[1][2].
CAS Number
786686-79-1
Product Name Alternative
LY170053-d3
UNSPSC
12352005
Hazard Statement
H301-H317-H319
Target
5-HT Receptor; Adrenergic Receptor; Apoptosis; Autophagy; Dopamine Receptor; mAChR; Mitophagy
Type
Isotope-Labeled Compounds
Related Pathways
Apoptosis; Autophagy; GPCR/G Protein; Neuronal Signaling
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease
Purity
99.09
Solubility
10 mM in DMSO|DMSO : 20mg/mL (ultrasonic)
Smiles
[2H]C(N1CCN(C2=NC3=CC=CC=C3NC4=C2C=C(C)S4)CC1)([2H])[2H]
Molecular Formula
C17H17D3N4S
Molecular Weight
315.45
Precautions
P261-P264-P270-P272-P280-P302+P352-P305+P351+P338-P330-P362+P364-P405-P501
References & Citations
[1]APPROVED AGREED-UPON LABELING.|[2]Olanzapine for Injection, powder, for solution for intramuscular use.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Isoform
5-HT2 Receptor;5-HT6 Receptor; D3 Receptor; mAChR1

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Alternative Products

CatalogName
CS-O-02882Olanzapine-d3
MBS5767229Olanzapine D3
sc-212470Olanzapine-methyl-d3
CS-O-10446Olanzapine N oxide-d3
TRC-O253772-1MGOlanzapine-d3 2-Carboxaldehyde
TRC-O253762-1MGOlanzapine-d3 N-Oxide
TRC-D230973-25MGN-Demethyl Olanzapine-d3
O5940-01-01Olanzapine-methyl-d3 discontinued
TRC-C369392-10MGN-Chloromethyl Olanzapine-d3 Chloride
CS-T-964052-Hydroxymethyl Olanzapine-d3 (Major)

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