Products for Research Use Only
RegisterLogin

NWL-117

CAT: 0804-HY-125194Size: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-125194Size:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
NWL-117 is a brain-penetrant and highly selective Caspase-6 (Casp6) inhibitor with an IC50 value of 192 nM. NWL-117 is promising for research of neurodegenerative diseases, particularly Alzheimer's disease and Huntington's disease [1].
CAS Number
2267318-43-2
UNSPSC
12352005
Target
Caspase
Related Pathways
Apoptosis
Field of Research
Neurological Disease
Smiles
O=C(O)[C@@H](/C=C/S(=O)(C)=O)NC([C@H]([C@@H](C)CC)NC([C@H](CCC(O)=O)NC([C@H](C(C)C)NC(OCC1=CC=CC=C1)=O)=O)=O)=O
Molecular Formula
C29H42N4O11S
Molecular Weight
654.73
References & Citations
[1]Pakavathkumar P, et al. Caspase vinyl sulfone small molecule inhibitors prevent axonal degeneration in human neurons and reverse cognitive impairment in Caspase-6-overexpressing mice. Mol Neurodegener. 2017 Feb 28;12 (1) :22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Related Products

CatalogName
HY-161785EGFR-IN-117
HY-176436SGW-117
HY-P991294MGTA-117 Antibody
HY-149307CYCA-117-70
HY-168066Antifungal agent 117
HY-W282615-01Antibacterial agent 117
HY-159860-01IR-117-17
HY-P5767Fibrinogen γ-chain (117-133)
HY-175460SARS-CoV-2-IN-117
HY-159683E3 Ligase Ligand-linker Conjugate 117

Alternative Products

CatalogName
MBS3606920NWL-117
T88785-01EGFR-IN-117
MBS3603992-01MIN-117
MBS3601679-01TAS-117
MBS5811021HA-117
BW167833WZB 117
T201180-01IR-117-17
T200652-01Antifungal agent 117
RM-L142717-01Linezolid Impurity 117
RM-P020417-01Palbociclib Impurity 117

Popular Products