C75 (Standard)

CAT: 0804-HY-12364R-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-12364R-01Size:1 mg
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
C75 (Standard) is the analytical standard of C75. This product is intended for research and analytical applications. C75 is a synthetic fatty-acid synthase (FASN) inhibitor; inhibits prostate cancer cells PC3 with an IC50 of 35 μM[1][2][3]. C75 is a potent CPT1A activator[5].
CAS Number
[218137-86-1]
UNSPSC
12352100
Target
Fatty Acid Synthase (FASN) ; Reference Standards
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cancer
Smiles
O=C(C(C1=C)C(CCCCCCCC)OC1=O)O
Molecular Formula
C14H22O4
Molecular Weight
254.32
References & Citations
[1]Rae C, et al. Inhibition of Fatty Acid Synthase Sensitizes Prostate Cancer Cells to Radiotherapy.|[2]Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+) -C75 is a strong anorectic drug; (-) -C75 has antitumor activity. Chirality. 2013 May;25 (5) :281-7.|[3]Gao S, et al. Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem. Proc Natl Acad Sci U S A. 2003 May 13;100 (10) :5628-33.|[4]Thupari JN, et al. C75 increases peripheral energy utilization and fatty acid oxidation in diet-induced obesity. Proc Natl Acad Sci U S A. 2002 Jul 9;99 (14) :9498-502.|[5] Yan Xue, et al. Inhibition of Carnitine Palmitoyltransferase 1A Aggravates Fatty Liver Graft Injury via Promoting Mitochondrial Permeability Transition. Transplantation. 2021 Mar 1;105 (3) :550-560.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

Related Products

CatalogName
HY-12364B-01(−) -C75
HY-12364-01C75
HY-12364C-01(+) -trans-C75
HY-12364A-01Trans-C75
HY-B0204R-01Pimobendan (Standard)
HY-B1493RBentiromide (Standard)
HY-121272RDifloxacin (Standard)
HY-B1860R-01Imazapic (Standard)
HY-B0397RDichlorphenamide (Standard)
HY-131102R-01Mequindox (Standard)

Alternative Products

CatalogName
abx098956-01Standard
ST-08004-02Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard + BRS Electrolyte
ST-80004-01Ascorbic Acid Standard + Gallic Acid Standard + TROLOX Standard for biological samples
RE21029ARAb Standard A (Standard 0) 20 ml
D95362Phosphorus Standard
D95339Magnesium Standard
D95223Glucose Standard
D06520SVCO2 Standard
5252-SSurrogate Standard
8260-IInternal Standard

Popular Products