(+) -trans-C75

• Description:

  (+) -trans-C75 ((+) -C75) is an enantiomer of C75 (HY-12364) (a fatty acid synthase inhibitor) . (+) -trans-C75 is less potent than the racemic mixture or the (-) enantiomer in enhancing the cancer-killing ability of ionizing radiation. (+) -trans-C75 inhibits CPT1 and is an anorectic agent[1][2].

• Product Name Alternative:

  (+) -C75

• UNSPSC:

  12352005

• Target:

  Mitochondrial Metabolism

• Type:

  Reference compound

• Related Pathways:

  Metabolic Enzyme/Protease

• Applications:

  Metabolism-sugar/lipid metabolism

• Field of Research:

  Others

• Assay Protocol:

  https://www.medchemexpress.com/plus-trans-c75.html

• Smiles:

  O=C([C@@H](C1=C)[C@@H](CCCCCCCC)OC1=O)O

• Molecular Formula:

  C14H22O4

• Molecular Weight:

  254.32

• References & Citations:

  [1]Rae C, et al. Differential in radiosensitizing potency of enantiomers of the fatty acid synthase inhibitor C75. Chirality. 2017 Jan;29 (1) :10-13.|[2]Makowski K, et al. Differential pharmacologic properties of the two C75 enantiomers: (+) -C75 is a strong anorectic drug; (-) -C75 has antitumor activity. Chirality. 2013 May;25 (5) :281-7.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  [1234694-20-2]