Products for Research Use Only
RegisterLogin

Troriluzole (hydrochloride)

CAT: 0804-HY-122487ASize: 1 EachDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-122487ASize:1 Each
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
Troriluzole hydrochloride is a third-generation peptide precursor of Riluzole and is an orally active glutamate modulator. Troriluzole hydrochloride can reduce synaptic glutamate levels and enhance the uptake of synaptic glutamate. Troriluzole hydrochloride shows potential for treating Alzheimer's disease and Generalized Anxiety Disorder (GAD)[2].
CAS Number
1926204-76-3
Product Name Alternative
BHV-4157 (hydrochloride)
UNSPSC
12352005
Target
MGluR
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C(CN(C)C(CNC(CN)=O)=O)NC1=NC2=CC=C(OC(F)(F)F)C=C2S1.Cl
Molecular Formula
C15H17ClF3N5O4S
Molecular Weight
455.84
References & Citations
[1]Schanzer B, et al. Novel investigational therapeutics for generalized anxiety disorder (GAD) . Expert Opin Investig Drugs. 2019 Nov;28 (11) :1003-1012.|[2]Huang LK, et al. Clinical trials of new drugs for Alzheimer disease. J Biomed Sci. 2020 Jan 6;27 (1) :18.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 3

Chemical Information

BHV-4157 hydrochloride
CAS Number1926204-76-3
PubChem CID133082858
IUPAC Name2-amino-N-[2-[methyl-[2-oxo-2-[[6-(trifluoromethoxy)-1,3-benzothiazol-2-yl]amino]ethyl]amino]-2-oxoethyl]acetamide;hydrochloride
Molecular FormulaC15H17ClF3N5O4S
Molecular Weight455.8
Topological Polar Surface Area155
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Heavy Atom Count29
Formal Charge0
Complexity595
SMILES
CN(CC(=O)NC1=NC2=C(S1)C=C(C=C2)OC(F)(F)F)C(=O)CNC(=O)CN.Cl
InChI
InChI=1S/C15H16F3N5O4S.ClH/c1-23(13(26)6-20-11(24)5-19)7-12(25)22-14-21-9-3-2-8(4-10(9)28-14)27-15(16,17)18;/h2-4H,5-7,19H2,1H3,(H,20,24)(H,21,22,25);1H
InChIKey
ZRZLEMQBDKNTLJ-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of BHV-4157 hydrochloride
CAS: 1926204-76-3
CID: 133082858
Formula: C15H17ClF3N5O4S
MW: 455.8
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight455.8
Hydrogen Bond Donor Count4
Hydrogen Bond Acceptor Count10
Rotatable Bond Count7
Exact Mass455.0641874
Monoisotopic Mass455.0641874
Topological Polar Surface Area155 Ų
Heavy Atom Count29
Formal Charge0
Complexity595
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count2
Compound Is CanonicalizedYes

Related Products

CatalogName
HY-122487-01Troriluzole
HY-B0500BAlverine (hydrochloride)
HY-W714513VU0469650 (hydrochloride)
HY-W708286-01α-Pyrrolidinobutiothiophenone (hydrochloride)
HY-W492795Quifenadine (hydrochloride)
HY-W012179-01Phenylpiperazine (hydrochloride)
HY-Z6449-01Phenylephrone (hydrochloride)
HY-W209279(±) Anabasine (hydrochloride)
HY-W027446-01Pyridoxal hydrochloride
HY-W011963-01Melevodopa (hydrochloride)

Alternative Products

CatalogName
GTR19113311-01Troriluzole hydrochloride
GTR19030377-01Troriluzole
300563Ligustrazine Hydrochloride (Chuanxiongzine hydrochloride)
D3190-91GDeoxynojirimycin Hydrochloride (DNJ Hydrochloride)
OR1043462-01Hydrochloride
MBS6103001-01O-Cyclopropylmethyl-hydroxylamine, Hydrochloride (Cyclopropylmethoxyamine, Hydrochloride, Cyclopropylmethoxylamine, Hydrochloride)
C7050-01Cysteamine hydrochloride; 2-AminoeThanethiol Hydrochloride; 2-Aminoethane-1-Thiol Hydrochloride; Mercaptamine Hydrochloride
P9050-45Propargylamine, Hydrochloride (2-Propynylamine, Hydrochloride)
46264200Thiamine hydrochloride (Vitamin B1 hydrochloride)
MBS6076243-01N-Butyldeoxynojirimycin, Hydrochloride (Miglustat, Hydrochloride)

Popular Products