Products for Research Use Only

Paroxetine (Standard)

CAT: 0804-HY-122272R-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:0804-HY-122272R-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Paroxetine (Standard) is the analytical standard of Paroxetine. This product is intended for research and analytical applications. Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs) . Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches[1][2][3][4].
CAS Number
61869-08-7
UNSPSC
12352100
Target
Adrenergic Receptor; Apoptosis; P2X Receptor; Reference Standards; Serotonin Transporter
Related Pathways
Apoptosis; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling; Others
Field of Research
Cancer; Neurological Disease
Purity
99.79
Smiles
FC1=CC=C(C=C1)[C@H]2[C@@H](CNCC2)COC3=CC=C4OCOC4=C3
Molecular Formula
C19H20FNO3
Molecular Weight
329.37
References & Citations
[1]M Bourin, et al. Paroxetine: a review. CNS Drug Rev. Spring 2001;7 (1) :25-47|[2]Young-Woo Cho, et al. Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation. Cancers (Basel) . 2019 Jan 9;11 (1) :64.|[3]Malek Zarei, et al. Paroxetine attenuates the development and existing pain in a rat model of neurophatic pain. Iran Biomed J. 2014;18 (2) :94-100.|[4]S Lightowler, et al. Anxiolytic-like effect of paroxetine in a rat social interaction test. Pharmacol Biochem Behav. 1994 Oct;49 (2) :281-5.
Shipping Conditions
Blue Ice
Storage Conditions
4°C, sealed and dry storage, away from light and moisture
Scientific Category
Reference Standards