Paroxetine

CAT: 0804-HY-122272-01Size: 10 mM - 1 mLDry Ice: NoHazardous: No

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CAT#:0804-HY-122272-01Size:10 mM - 1 mL

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Description

Paroxetine is an oral inhibitor that falls under the category of selective serotonin reuptake inhibitors (SSRIs) . Paroxetine is also a very weak norepinephrine (NE) reuptake inhibitor, capable of inducing cell apoptosis and having anti-tumor activity. Paroxetine has antidepressant, anti-anxiety, and pain-relieving effects, and it can help improve conditions like obsessive-compulsive disorder, panic disorder, post-traumatic stress disorder, premenstrual anxiety, and chronic headaches[1][2][3][4].

CAS Number

61869-08-7

Product Name Alternative

BRL29060

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Adrenergic Receptor; Apoptosis; P2X Receptor; Serotonin Transporter

Type

Reference compound

Related Pathways

Apoptosis; GPCR/G Protein; Membrane Transporter/Ion Channel; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Cancer; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/paroxetine.html

Purity

99.94

Solubility

DMSO : 50 mg/mL (ultrasonic)

Smiles

FC1=CC=C(C=C1)[C@H]2[C@@H](CNCC2)COC3=CC=C4OCOC4=C3

Molecular Formula

C19H20FNO3

Molecular Weight

329.37

Precautions

H302, H315, H319, H335

References & Citations

[1]M Bourin, et al. Paroxetine: a review. CNS Drug Rev. Spring 2001;7 (1) :25-47|[2]Young-Woo Cho, et al. Paroxetine Induces Apoptosis of Human Breast Cancer MCF-7 Cells through Ca2+-and p38 MAP Kinase-Dependent ROS Generation. Cancers (Basel) . 2019 Jan 9;11 (1) :64.|[3]Malek Zarei, et al. Paroxetine attenuates the development and existing pain in a rat model of neurophatic pain. Iran Biomed J. 2014;18 (2) :94-100.|[4]S Lightowler, et al. Anxiolytic-like effect of paroxetine in a rat social interaction test. Pharmacol Biochem Behav. 1994 Oct;49 (2) :281-5.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, protect from light)

Scientific Category

Reference compound1

Clinical Information

Launched

Citation 01

Alternative Products

Catalog	Name
BA5103-100	Paroxetine
B2252-5.1	Paroxetine HCl
B6952-10	Paroxetine maleate
C8698-100	Paroxetine Mesylate
318458	Paroxetine Hydrochloride
CS-O-52372	Paroxetine-D3

Paroxetine

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