2-Bromo-LSD

• Description:

  2-Bromo-LSD (BOL-148; Bromolysergide) is a Dopamine Receptor antagonist that directly affects dopamine neurons in the substantia nigra neostriatum. 2-Bromo-LSD increases the hydroxylation of tyrosine in striatum and antagonizes the decrease of Apomorphine-induced DOPA accumulation. 2-Bromo-LSD also blocks the 5-HT Receptor mediated DOPA formation[1].

• Product Name Alternative:

  BOL-148; Bromolysergide

• UNSPSC:

  12352005

• Hazard Statement:

  H225, H302+H312+H332, H319

• Target:

  5-HT Receptor; Dopamine Receptor

• Related Pathways:

  GPCR/G Protein; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Purity:

  97.26

• Solubility:

  10 mM in DMSO

• Smiles:

  [H][C@]1(C2)N(C[C@@H](C=C1C3=CC=CC4=C3C2=C(N4)Br)C(N(CC)CC)=O)C

• Molecular Formula:

  C20H24BrN3O

• Molecular Weight:

  402.33

• Precautions:

  H225, H302+H312+H332, H319

• References & Citations:

  [1]Persson SA. The effect of LSD and 2-bromo LSD on the striatal DOPA accumulation after decarboxylase inhibition in rats. Eur J Pharmacol. 1977 May 1;43 (1) :73-83.

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  -20°C (Powder, protect from light, stored under nitrogen)

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  478-84-2