2′-Bromo-2′-deoxyuridine

2′-Bromo-2′-deoxyuridine

• CAS Number: 4753-02-0
• UNSPSC Description: 2′-Bromo-2′-deoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
• Target Antigen: Nucleoside Antimetabolite/Analog
• Type: Reference compound
• Related Pathways: Cell Cycle/DNA Damage
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/2-bromo-2-deoxyuridine.html
• Purity: 96.92
• Solubility: DMSO : 200 mg/mL (ultrasonic)
• Smiles: OC[C@@H]1[C@@H](O)[C@@H](Br)[C@H](N2C(NC(C=C2)=O)=O)O1
• Molecular Weight: 307.10
• References & Citations: [1]Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.
• Shipping Conditions: Room Temperature
• Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
• Clinical Information: No Development Reported