2-Bromo-2'-methoxyacetophenone

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804-HY-W012267

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CAS Number: 31949-21-0
UNSPSC Description: 2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, that inhibits MurA in E. coli with an IC50 of 0.38 μM. 2-Bromo-2'-methoxyacetophenone can be used in antibacterial research for blocking bacterial cell wall synthesis[1].
Target Antigen: Bacterial
Type: Reference compound
Related Pathways: Anti-infection
Field of Research: Infection
Assay Protocol: https://www.medchemexpress.com/2-bromo-2-methoxyacetophenone.html
Purity: 99.11
Smiles: COC1=CC=CC=C1C(CBr)=O
Molecular Weight: 229.07
References & Citations: [1]Mihalovits LM, et al., Catalytic Mechanism and Covalent Inhibition of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA): Implications to the Design of Novel Antibacterials. J Chem Inf Model. 2019 Dec 23;59(12):5161-5173.
Shipping Conditions: Room Temperature
Storage Conditions: -20°C, 3 years; 4°C, 2 years (Powder)
Clinical Information: No Development Reported

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