2-Bromo-2'-methoxyacetophenone

• UNSPSC Description:

  2-Bromo-2'-methoxyacetophenone is an irreversible inhibitor for MurA, that inhibits MurA in E. coli with an IC50 of 0.38 μM. 2-Bromo-2'-methoxyacetophenone can be used in antibacterial research for blocking bacterial cell wall synthesis[1].

• Target Antigen:

  Bacterial

• Type:

  Reference compound

• Related Pathways:

  Anti-infection

• Field of Research:

  Infection

• Assay Protocol:

  https://www.medchemexpress.com/2-bromo-2-methoxyacetophenone.html

• Purity:

  99.11

• Smiles:

  COC1=CC=CC=C1C(CBr)=O

• Molecular Weight:

  229.07

• References & Citations:

  [1]Mihalovits LM, et al., Catalytic Mechanism and Covalent Inhibition of UDP-N-Acetylglucosamine Enolpyruvyl Transferase (MurA): Implications to the Design of Novel Antibacterials. J Chem Inf Model. 2019 Dec 23;59(12):5161-5173.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Clinical Information:

  No Development Reported

• CAS Number:

  31949-21-0