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Hexoprenaline (sulfate)

CAT: 0804-HY-121185ASize: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-121185ASize:1 Each
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Description
Hexoprenaline sulfate is an orally active and selective β-adrenergic receptor agonist. Hexoprenaline sulfate can dilate the bronchi. Hexoprenaline sulfate can activate adenylate cyclase and increases 14C-Aminopyrine uptake. Hexoprenaline sulfate exhibits anti-infection and anti-inflammmation effect. Hexoprenaline sulfate can increase placental weight and blood flow. Hexoprenaline sulfate can be used for the researches of inflammation, immunology, infection, endocrinology and neurological disease, such as asthma, chronic bronchitis, sepsis and intoxication of organophosphorus compounds[1][2][3][4][5].
CAS Number
32266-10-7
UNSPSC
12352005
Hazard Statement
H331-H412
Target
Adrenergic Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Infection; Endocrinology; Inflammation/Immunology; Neurological Disease
Solubility
10 mM in DMSO
Smiles
OC(CNCCCCCCNCC(O)C1=CC=C(C(O)=C1)O)C2=CC=C(C(O)=C2)O.OS(O)(=O)=O
Molecular Formula
C22H34N2O10S
Molecular Weight
518.58
Precautions
P261-P271-P273-P304+P340-P403+P233-P405-P501
References & Citations
[1]Schonell M, et al. Bronchodilator effect of hexoprenaline aerosol in bronchial asthma and chronic bronchitis. Med J Aust. 1977 Dec 17;2 (25) :828-30.|[2]Ruoff HJ, et al. Adrenergic stimulation of isolated rat gastric mucosal cells. Effect on adenylate cyclase and 14C-aminopyrine uptake. Naunyn Schmiedebergs Arch Pharmacol. 1982 Aug;320 (2) :175-81.|[3]Zabrodskii P F. et al. The Mechanisms of the Cholinergic Anti-Inflammatory Pathway after Acute Intoxication of Organophosphorus Compounds[J]. Biomedical Journal, 2010, 1: 5.|[4]Zabrodskii P F. et al. The influence of various drugs on mortality of mice and the concentration of proinflammatory cytokines in blood at sepsis caused by E. coli[J]. Acta scientific microbiology, 2018, 1: 11-14.|[5]Lipshitz J, et al. Effect of long-term administration of beta 2-sympathomimetic drug in the diet-restricted pregnant rat model. Am J Obstet Gynecol. 1986 Feb;154 (2) :314-7.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
β adrenergic receptor

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