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Darapladib analog-1

CAT: 0804-HY-120849Size: 1 EachDry Ice: NoHazardous: No
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CAT#:0804-HY-120849Size:1 Each
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Darapladib analog-1 (Compound 16) is an O-alkylated Darapladib. Darapladib analog-1 inhibits Lp-PLA2. Darapladib analog-1 can be used in the research of atherosclerosis[1].
CAS Number
1389264-17-8
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Drug Derivative; Phospholipase
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Cardiovascular Disease
Smiles
O=C(COC1=NC(SCC2=CC=C(C=C2)F)=NC3=C1CCC3)N(CCN(CC)CC)CC4=CC=C(C5=CC=C(C(F)(F)F)C=C5)C=C4
Molecular Formula
C36H38F4N4O2S
Molecular Weight
666.77
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Guibbal F, et al. Regioselectivity of thiouracil alkylation: Application to optimization of Darapladib synthesis. Bioorg Med Chem Lett. 2018 Feb 15;28 (4) :787-792.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Phospholipase A

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