Piretanide-d4

• Description:

  Piretanide-d4 is the deuterium labeled Piretanide. Piretanide is an oral active, relatively safe and effective diuretic. Piretanide has the potential for the research of congestive heart failure with a potential advantage of having potassium-sparing properties. Piretanide can also be used for the research of hypertension[1][2].

• UNSPSC:

  12352005

• Target:

  Isotope-Labeled Compounds

• Related Pathways:

  Others

• Field of Research:

  Cardiovascular Disease

• Solubility:

  10 mM in DMSO

• Smiles:

  O(C1=C(C=C(C(O)=O)C=C1S(N)(=O)=O)N2C(CCC2([2H])[2H])([2H])[2H])C3=CC=CC=C3

• Molecular Formula:

  C17H14D4N2O5S

• Molecular Weight:

  366.42

• References & Citations:

  [1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Carda-Broch S, et al. Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection. J Chromatogr Sci. 1999;37 (4) :93-102. |[3]Sherman LG, et al. Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure. Clin Pharmacol Ther. 1986;40 (5) :587-594.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Isotope-Labeled Compounds

• Clinical Information:

  No Development Reported

• CAS Number:

  [1246816-90-9]