Piretanide-d4

CAT: 0804-HY-119816S-01Size: 1 mgDry Ice: NoHazardous: No
CAT#:0804-HY-119816S-01Size:1 mg
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Description
Piretanide-d4 is the deuterium labeled Piretanide. Piretanide is an oral active, relatively safe and effective diuretic. Piretanide has the potential for the research of congestive heart failure with a potential advantage of having potassium-sparing properties. Piretanide can also be used for the research of hypertension[1][2].
CAS Number
[1246816-90-9]
UNSPSC
12352005
Target
Isotope-Labeled Compounds
Related Pathways
Others
Field of Research
Cardiovascular Disease
Solubility
10 mM in DMSO
Smiles
O(C1=C(C=C(C(O)=O)C=C1S(N)(=O)=O)N2C(CCC2([2H])[2H])([2H])[2H])C3=CC=CC=C3
Molecular Formula
C17H14D4N2O5S
Molecular Weight
366.42
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53 (2) :211-216. |[2]Carda-Broch S, et al. Analysis of urine samples containing cardiovascular drugs by micellar liquid chromatography with fluorimetric detection. J Chromatogr Sci. 1999;37 (4) :93-102. |[3]Sherman LG, et al. Piretanide, a potent diuretic with potassium-sparing properties, for the treatment of congestive heart failure. Clin Pharmacol Ther. 1986;40 (5) :587-594.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported

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