FE-999024

• Description :

  FE-999024 (CH-2856) is a specific tissue kallikrein inhibitor. FE-999024 can inhibit cancer cells invasion with a maximum of 39%. FE-999024 can reduce eosinophilia in a model of allergic inflammation. FE-999024 can be used for the researches of cancer, inflammation and immunology[1][2].

• CAS Number :

  [168825-65-8]

• Product Name Alternative :

  CH-2856

• UNSPSC :

  12352005

• Target :

  Kallikrein

• Related Pathways :

  Immunology/Inflammation

• Applications :

  COVID-19-immunoregulation

• Field of Research :

  Cancer; Inflammation/Immunology

• Smiles :

  O=C(N)[C@H](CC1=C2C=CC=CC2=CC=C1)N(C([C@@H](CC3=CC=C(Cl)C=C3)N)=O)CCCNC(N)=N

• Molecular Formula :

  C26H31ClN6O2

• Molecular Weight :

  495.02

• References & Citations :

  [1]Wolf WC, et al. A synthetic tissue kallikrein inhibitor suppresses cancer cell invasiveness. Am J Pathol. 2001 Nov;159 (5) :1797-805.|[2]Evans DM, et al. Synthetic inhibitors of human tissue kallikrein. Immunopharmacology. 1996 May;32 (1-3) :117-8.

• Shipping Conditions :

  Room temperature

• Scientific Category :

  Reference compound1

• Clinical Information :

  No Development Reported