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RLX (hydrochloride)

CAT: 0804-HY-116604ASize: 1 EachDry Ice: NoHazardous: No
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Description
RLX (PD 139530) hydrochloride is the hydrochloride of RLX. RLX is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness[1].
CAS Number
21314-60-3
Product Name Alternative
PD 139530 (hydrochloride)
UNSPSC
12352005
Target
Akt; PI3K
Related Pathways
PI3K/Akt/mTOR
Field of Research
Cancer
Smiles
O=C1C2=C(N=C3N1CCCCC3)C=CC=C2.Cl
Molecular Formula
C13H15ClN2O
Molecular Weight
250.72
References & Citations
[1]Qazi AK, et al. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer. Cancer Lett. 2015 Apr 1;359 (1) :47-56.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

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