Products for Research Use Only
RegisterLogin

RLX

CAT: 0804-HY-116604-01Size: 1 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0804-HY-116604-01Size:1 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
RLX (PD 139530) is a PI3K/Akt/FoxO3a signaling inhibitor, possessing significant therapeutic potential in experimental colon cancer. RLX can effectively modulate the tumor microenvironment, enhancing the efficacy of cancer immunotherapy. RLX demonstrates the ability to improve the retention time of therapeutic agents within the tumor microenvironment by utilizing advanced nanoparticle delivery systems. RLX can be integrated with various treatment modalities, such as chemotherapy and radiotherapy, to enhance overall tumor therapy effectiveness[1].
CAS Number
4425-23-4
Product Name Alternative
PD 139530
UNSPSC
12352005
Hazard Statement
H302-H315-H319-H335
Target
Akt; PI3K
Type
Reference compound
Related Pathways
PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/rlx.html
Smiles
O=C1N2C(CCCCC2)=NC3=C1C=CC=C3
Molecular Formula
C13H14N2O
Molecular Weight
214.26
Precautions
P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
References & Citations
[1]Qazi AK, et al. Quinazoline based small molecule exerts potent tumour suppressive properties by inhibiting PI3K/Akt/FoxO3a signalling in experimental colon cancer. Cancer Lett. 2015 Apr 1;359 (1) :47-56.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported

Alternative Products

CatalogName
CN-A038-500GMAgar, Micropropagation - Type I (Gracilaria)
M2302-20HPhaseShield™ Gel Tubes, Heavy (200x 2ml)
M2302-20LPhaseShield™ Gel Tubes, Light (200x 2ml)
E-EL-M0380ELISA kit for Mouse CDKN1B (Cyclin Dependent Kinase Inhibitor 1B)
E-KAB-0415Human CA9 Antibody Pair Set
E-KAB-0614Porcine IL-2 Antibody Pair Set
PKSH030904Recombinant Human Purine nucleoside phosphorylase/PNP Protein (His Tag)
E-EL-P0403ELISA kit for Porcine MUC3 (Mucin 3)
E-EL-H2307ELISA kit for Human TL1A (Tumor Necrosis Factor Related Ligand 1A)
PKSH031652Recombinant Human IFNAR2/IFNABR Protein (Fc Tag)

Popular Products