(rac) -K20

• Description:

  (rac) -K20 is the racemate of K20, a KRas G12C inhibitor with an IC50 of 1.16 μM. K20 has antitumor activity[1].

• UNSPSC:

  12352005

• Target:

  Others

• Related Pathways:

  Others

• Field of Research:

  Cancer

• Smiles:

  C=C (C (N1CCN (C (C1) C) C2=NC=NC3=C (C (C4=CC (Cl) =CC=C4OC) =C (C=C23) Cl) F) =O) C (F) (F) F

• Molecular Formula:

  C24H20Cl2F4N4O2

• Molecular Weight:

  543.34

• References & Citations:

  [1]Zhao H, et al. Discovery of ARS-1620 analogs as KRas G12C inhibitors with high in vivo antitumor activity. Bioorg Chem. 2022 Apr;121:105652.

• Shipping Conditions:

  Room temperature

• Scientific Category:

  Reference compound1

• Clinical Information:

  No Development Reported

• CAS Number:

  2915618-92-5