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Methyl mycophenolate (Standard)

CAT: 0804-HY-113972RSize: 1 EachDry Ice: NoHazardous: No
CAT#:0804-HY-113972RSize:1 Each
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Description
Avanafil (Standard) is the analytical standard of Avanafil. This product is intended for research and analytical applications. Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis[1][2][3].
CAS Number
[31858-66-9]
UNSPSC
12352005
Target
Others; Reference Standards
Related Pathways
Others
Field of Research
Inflammation/Immunology
Smiles
O=C(OC)CC/C(C)=C/CC1=C(O)C2=C(COC2=O)C(C)=C1OC
Molecular Formula
C18H22O6
Molecular Weight
334.37
References & Citations
[1] Elsebai MF. Secondary metabolites from the marine-derived fungus Phaeosphaeria spartinae. Nat Prod Res. 2019 Aug 23:1-6.|[2]Gainer FE, et al. Thin-layer chromatography of mycophenolic acid and related compounds. J Chromatogr. 1971 Feb 3;54 (3) :446-8.
Shipping Conditions
Room temperature
Scientific Category
Reference Standards

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