Mycophenolate mofetil (hydrochloride)

Mycophenolate mofetil (hydrochloride)

• CAS Number: 116680-01-4
• UNSPSC Description: Mycophenolate mofetil (RS 61443) hydrochloride is a immunosuppressant, a non-competitive, selective and reversible inhibitor of inosine monophosphate dehydrogenase (IMPD) type I/II with IC50s of 39 nM and 27 nM, respectively.
• Target Antigen: Bacterial; Endogenous Metabolite
• Type: Reference compound
• Related Pathways: Anti-infection;Metabolic Enzyme/Protease
• Applications: Cancer-programmed cell death
• Field of Research: Cancer
• Assay Protocol: https://www.medchemexpress.com/mycophenolate-mofetil-hydrochloride.html
• Purity: 99.17
• Solubility: 10 mM in DMSO
• Smiles: O=C(OCCN1CCOCC1)CC/C(C)=C/CC2=C(O)C3=C(COC3=O)C(C)=C2OC.Cl
• Molecular Weight: 469.96
• References & Citations: [1]Nakanishi, T., et al., Effect of the inosine 5'-monophosphate dehydrogenase inhibitor BMS-566419 on rat cardiac allograft rejection. Int Immunopharmacol, 2010. 10(1): p. 91-7.|[2]Dehghani, F., et al., Inhibition of microglial and astrocytic inflammatory responses by the immunosuppressant mycophenolate mofetil. Neuropathol Appl Neurobiol, 2010. 36(7): p. 598-611.|[3]Ozgen, M., et al., Mycophenolate mofetil and daclizumab targeting T lymphocytes in bleomycin-induced experimental scleroderma. Clin Exp Dermatol, 2012. 37(1): p. 48-54.
• Shipping Conditions: Room Temperature
• Storage Conditions: 4°C (Powder, protect from light, stored under nitrogen)
• Clinical Information: Launched